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Opioids

Researchers identify key brain circuits for reward-seeking and avoidance behavior

From NIH. Previously unrecognized pathways in mice have relevance for mental health and addiction research. Researchers have identified connections between neurons in brain systems associated with reward, stress, and emotion. Conducted in mice, the new study may help untangle multiple psychiatric conditions, including alcohol use disorder, anxiety disorders, insomnia, and depression in humans. “Understanding these […]


Notification of patient overdose deaths reduces clinician opioid prescriptions

From NIH. NIH-funded study shows clinicians reduced prescriptions following behavioral “nudge.” Clinicians were more likely to reduce the number and dose of opioid drugs they prescribed after learning that one of their patients had died from an overdose from a controlled substance than those not notified, according to a recent study appearing in the August […]


PA Law to Require Notification on Drug-Exposed Babies

From the Chronicle of Social Change. New Pennsylvania Law Requires Notifications on All Drug-Exposed Babies by Marisol Zarate The Pennsylvania Department of Human Services will hear about every child born in the state that is exposed to drugs at birth, thanks to a bill signed into law this month by Gov. Tom Wolf (D). According to […]


Effective Treatments for Opioid Use Disorder Are Underutilized

From NIH. NIH research confirms effective treatments for opioid use disorder are underutilized A National Institutes of Health-funded study found that treatment of opioid use disorder with either methadone or buprenorphine following a nonfatal opioid overdose is associated with significant reductions in opioid related mortality. The research, published today in the Annals of Internal Medicine, was […]


Attorney General Jeff Sessions announces Operation Synthetic Opioid Surge to combat crisis

From Healthcare Finance. Operation S.O.S. was inspired by prosecution efforts in Manatee County, Florida, which realized a 77 percent drop in overdose deaths. By Susan Moore Attorney General Jeff Sessions chose Maine as one of his stops to promote the newly-announced operation Synthetic Opioid Surge or S.O.S., because the state is among 10 areas of […]


Overdose Deaths with Carfentanil and Other Fentanyl Analogs Detected — 10 States

From CDC MMWR. O’Donnell J, Gladden RM, Mattson CL, Kariisa M. Notes from the Field: Overdose Deaths with Carfentanil and Other Fentanyl Analogs Detected — 10 States, July 2016–June 2017. MMWR Morb Mortal Wkly Rep 2018;67:767–768. DOI: http://dx.doi.org/10.15585/mmwr.mm6727a4. Notes from the Field: Overdose Deaths with Carfentanil and Other Fentanyl Analogs Detected — 10 States, July 2016–June 2017 Fentanyl and […]


MMWR: MRSA among persons who inject drugs

From CDC. Invasive Methicillin-Resistant Staphylococcus aureus Infections Among Persons Who Inject Drugs — Six Sites, 2005–2016 June 8, 2018 / 67(22);625-628 In the United States, age-adjusted opioid overdose death rates increased by >200% during 1999–2015, and heroin overdose death rates increased nearly 300% during 2011–2015 (1). During 2011–2013, the rate of heroin use within the past year […]


Naloxone Recall—Two Lots From Hospira Recalled Due to Particulate Matter

Recall from the FDA Hospira Issues a Voluntary Nationwide Recall for Two Lots of Naloxone Hydrochloride Injection, USP, in the Carpuject™ Syringe System due to the Potential Presence of Particulate Matter   Hospira, Inc., a Pfizer company, is voluntarily recalling lots 72680LL and 76510LL of Naloxone Hydrochloride Injection, USP, 0.4 mg/mL, 1 mL in 2.5 mL, […]


Did big pharma hide opioid addiction?

From the New York Times Origins of an Epidemic: Purdue Pharma Knew Its Opioids Were Widely Abused by Barry Meier Purdue Pharma, the company that planted the seeds of the opioid epidemic through its aggressive marketing of OxyContin, has long claimed it was unaware of the powerful opioid painkiller’s growing abuse until years after it […]